Phenylpiracetam vs Piracetam
Users often take Phenylpiracetam as a Nootropic substance with similar effects to Piracetam. Studies have found that it is effective at preventing cognitive decline. This means that it can help to improve brain function, especially in people who suffer from dementia or stroke.
People take phenylpiracetam because it is said to act as a brain-boosting stimulant, and to aid in memory and learning. It is a banned substance by the World Anti-Doping Agency (WADA) due to its apparent brain-boosting and Nootropic effects, as well as giving users resistance to cold.[1]
Phenylpiracetam produces resistance to coldThere are a number of studies that have been done on Phenylpiracetam’s apparent ability to boost cognitive power and prevent cognitive decline. Most of these studies were conducted in Russia, and a lot of them are not available on Western scientific journal websites.[2]
Studies have also found that phenylpiracetam may be effective as an anti-anxiety / anti-depression substance, as well as having stimulant-like effects (increased alertness and energy).[3]
Stacking with Choline Bitartrate
Phenylpiracetam is said to increase memory and learning capabilitiesReading through blogs and forums, you’ll find a lot of information about stacking phenylpiracetam with choline bitartrate. This is apparently done to ‘replace lost acetylcholine’ from using phenylpiracetam / piracetam. However, examining scientific literature we find that the method of action of piracetam and phenylpiracetam do not seem to be closely related to acetylcholine.
People often take phenylpiracetam is thought to work in a similar way to piracetam. Phenylpiracetam is just piracetam with an added phenyl- group, which is thought to improve its bioavailability and potency. The truth is, the exact method of action of piracetam and phenylpiracetam is not yet fully understood.
The effects of piracetam (and, theoretically, also phenylpiracetam) appear to involve three main aspects:
- The substance seems to increase blood flow in the brain (stimulatory effects?)[4]
- It seems to preserve membrane fluidity (this may aid in brain-boosting properties and protecting the brain!)[5]
- It allows more glucose to be used by the brain (stimulatory effects?)[6]
After examining the proposed ways that these compounds work, we’ve decided that stacking with Choline would probably not have a major effect on the action of phenylpiracetam. However, using the two together could potentially provide a synergistic stack.
We definitely promote Choline Bitartrate, and we believe that this substance also has a wide range of Nootropic effects. For more information on Choline, please check out our product description here. We’ll also have some blog posts about Choline coming up in the next few months.
Liftmode Phenylpiracetam - 99%+ purityPhenylpiracetam Side Effects
It is quite hard to find a lot of good information about the side effects of phenylpiracetam since there is still a fair amount of research that could go into this substance. It appears that side effects when people take phenylpiracetem are mild and user specific. Some users report headaches, while others have claimed it makes them more thirsty or that they have trouble sleeping.[7]
Phenylpiracetam is very similar to its parent chemical, piracetam. Piracetam has a number of side effects, also mostly quite mild. These include short-lived effects of anxiety, restlessness and difficulty sleeping.[8]
When you take Phenylpiracetam, side effects may increase with increased doses. This is the same for all Nootropics.
User reports on How To Take Phenylpiracetam
People seem to have various methods of taking phenylpiracetam. Some prefer to take a phenylpiracetam sublingual dose, others are more keen to put it into a capsule to avoid the taste, and some just take it as is.
“Have been taking phenylpiracetam orally in 100mg doses, 1-3 times a day, for 4 months now… Phenylpiracetam has to be the strongest legal nootropic I have ever experienced. I put it into pill capsules to avoid the taste and I usually feel it within 30 minutes to an hour after taking it…
Positive effects experienced: Euphoria, increased motivation, increased concentration, quicker learning, reduced stress, increased memory, increased motor skills, increased physical endurance, and tolerance to the cold.
Negative effects experienced: Insomnia, tolerance, dehydration, trouble sleeping.” – Phenylpiracetam review on drugs-forum.com6
“The following day I had 200mg and later another 200mg. I was very alert and productive at work and certainly needed no coffee to pick me up. I work a lot of night shifts so this is excellent stuff for staying alert. Although that night I did not get much sleep, the following day I was surprised to wake up feeling very refreshed and ready to go.
The next day I decided to try 400mg in one dose. WOW holy jeebus I was impressed to find that after an hour had passed I was extremely alert, focused and at times borderlining on pleasant euphoria. There was a fleeting anxiety at this dose, but then I am prone to a small degree of anxiety (too much caffeine doesn't sit well with me) but this was tolerable. At times I did feel as though I could not sit still and needed to be doing something...” – Phenylpiracetam review on LongeCity.com[9]
References:
[1] Phenylpiracetam, Examine.com, available from: https://examine.com/supplements/phenylpiracetam/#ref8
[2] Savchenko AIu, Zakharova NS, Stepanov IN, [The phenotropil treatment of the consequences of brain organic lesions], Zh Nevrol Psikhiatr Im S S Korsakova. 2005;105(12):22-6, available from: http://www.ncbi.nlm.nih.gov/pubmed/16447562
[3] Zvejniece L et al., Investigation into stereoselective pharmacological activity of phenotropil., Basic Clin Pharmacol Toxicol. 2011 Nov;109(5):407-12. doi: 10.1111/j.1742-7843.2011.00742.x. Epub 2011 Jul 20., available from: http://www.ncbi.nlm.nih.gov/pubmed/21689376
[4] Akopian VP, Balian LS., [Mechanism of action of piracetam on cerebral circulation]., Farmakol Toksikol. 1987 Jan-Feb;50(1):38-41., available from: http://www.ncbi.nlm.nih.gov/pubmed/3556550
[5] Müller WE, Eckert GP, Eckert A, Piracetam: novelty in a unique mode of action., Pharmacopsychiatry. 1999 Mar;32 Suppl 1:2-9., available from: http://www.ncbi.nlm.nih.gov/pubmed/10338102
[6] Domańska-Janik K, Zaleska M., The action of piracetam on 14C-glucose metabolism in normal and posthypoxic rat cerebral cortex slices., Pol J Pharmacol Pharm. 1977 Mar-Apr;29(2):111-6., available from:
http://www.ncbi.nlm.nih.gov/pubmed/870885
[7] Phenylpiracetam Review (Phenotropil or Carphedon), baconpwnage2, review on Drugs-Forum.com, full review from: https://drugs-forum.com/forum/showthread.php?t=235782
[8] Piracetam, Examine.com, available from: http://examine.com/supplements/piracetam/
[9] Another Phenylpiracetam review, posted by pinnacle, October 2013, full review from: http://www.longecity.org/forum/topic/66678-another-phenylpiracetam-review/
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